Biology & Life Sciences Basics
Fundamental principles and concepts
MITx_PRO: Principles of Biomanufacturing: Using Biotechnology to Manufacture Medicines
Develop an integrated understanding of the creation of bio pharmaceuticals and how decisions made as early as product discovery can impact how a biologic is manufactured and delivered.
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Course Insight
Suitable for beginner learners. This course serves as an entry point into Biology & Life Sciences, building foundational knowledge before moving on to advanced frameworks or specialized paths.
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What You’ll Learn
- Discover how small changes in a protein therapeutic may change its efficacy, safety and manufacturability..
- Understand the method by which living cells are engineered to produce complex therapeutic proteins..
- Explore the way in which reactors are designed to support the growth of living cells that produce a target therapeutic..
- Learn how protein therapeutics are purified and how previous manufacturing steps inform how this is performed..
- Identify the keys to manufacture biopharmaceuticals in a regulated environment and analyze examples and case studies highlighting key biomanufacturing challenges..
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Description
The successful manufacturing of biologic medicines requires strong collaboration among multiple functional groups. Yet, many organizations are heavily siloed and fragmented communication across divisions can slow progress towards producing medicines for patients. Could your organization be working more effectively and efficiently?Using an applied case study, the program offers scientists, chemists, researchers, program managers, and other biological medicine specialists an opportunity to build an integrated understanding to their role in biomanufacturing.By the end of this course, you will understand how decisions made as early as product discovery can impact how a biologic is manufactured and delivered. You will also be able to answer questions such as:
How do you design biopharmaceutical medicines to be both effective and manufacturable?
How do you co-op cellular machinery to produce life-saving medicines?
How do you design reactors to keep the cellular factories happy and productive?
How do you remove cellular debris for the highest quality and most efficacious therapy?
Faster decision times could add risks associated with accelerated development of compounds, so how do you do all of this as efficiently as possible in a highly regulated environment?
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